BDBM50443288 CHEMBL3087954
SMILES: O=C(O[C@H]1C[N+]2(Cc3cc(no3)-c3ccccc3)CCC1CC2)C1(CCCCCC1)C1=CC=CC1
InChI Key: InChIKey=XRHBTBUUJLJXQO-JUEZVXFGSA-N
Data: 1 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M3 (Cavia porcellus) | BDBM50443288 (CHEMBL3087954) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 0.316 | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contracti... | Bioorg Med Chem Lett 23: 6248-53 (2013) Article DOI: 10.1016/j.bmcl.2013.09.092 BindingDB Entry DOI: 10.7270/Q2QF8VBG | |||||||||||
More data for this Ligand-Target Pair |