BDBM50443330 CHEMBL3086014

SMILES: COc1ccc(cc1-c1ccc(CNS(=O)(=O)c2c(C)noc2C)cc1)C#N

InChI Key: InChIKey=KGDQHXQPIXGHBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50443330 (CHEMBL3086014) Show SMILES COc1ccc(cc1-c1ccc(CNS(=O)(=O)c2c(C)noc2C)cc1)C#N Show InChI InChI=1S/C20H19N3O4S/c1-13-20(14(2)27-23-13)28(24,25)22-12-15-4-7-17(8-5-15)18-10-16(11-21)6-9-19(18)26-3/h4-10,22H,12H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from GST-tagged human mineralocorticoid receptor ligand binding domain after 4 hrs by liquid scintillation counting				Bioorg Med Chem Lett 23: 6239-42 (2013) Article DOI: 10.1016/j.bmcl.2013.09.099 BindingDB Entry DOI: 10.7270/Q2JQ12FV
					More data for this Ligand-Target Pair