BDBM50444284 CHEMBL3093637::US9649309, Compound UNC2084A

SMILES: CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NCC2CCNCC2)n1

InChI Key: InChIKey=CSTHTXUPJYUFSY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444284 (CHEMBL3093637 | US9649309, Compound UNC2084A) Show SMILES CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NCC2CCNCC2)n1 Show InChI InChI=1S/C25H37N7O4S/c1-2-3-10-27-25-29-18-22(23(31-25)28-17-19-8-11-26-12-9-19)24(33)30-20-4-6-21(7-5-20)37(34,35)32-13-15-36-16-14-32/h4-7,18-19,26H,2-3,8-17H2,1H3,(H,30,33)(H2,27,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9693-700 (2014) Article DOI: 10.1021/jm4013888 BindingDB Entry DOI: 10.7270/Q21G0NQ1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444284 (CHEMBL3093637 | US9649309, Compound UNC2084A) Show SMILES CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NCC2CCNCC2)n1 Show InChI InChI=1S/C25H37N7O4S/c1-2-3-10-27-25-29-18-22(23(31-25)28-17-19-8-11-26-12-9-19)24(33)30-20-4-6-21(7-5-20)37(34,35)32-13-15-36-16-14-32/h4-7,18-19,26H,2-3,8-17H2,1H3,(H,30,33)(H2,27,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...				US Patent US9649309 (2017) BindingDB Entry DOI: 10.7270/Q26Q209H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50444284 (CHEMBL3093637 | US9649309, Compound UNC2084A) Show SMILES CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NCC2CCNCC2)n1 Show InChI InChI=1S/C25H37N7O4S/c1-2-3-10-27-25-29-18-22(23(31-25)28-17-19-8-11-26-12-9-19)24(33)30-20-4-6-21(7-5-20)37(34,35)32-13-15-36-16-14-32/h4-7,18-19,26H,2-3,8-17H2,1H3,(H,30,33)(H2,27,28,29,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh Curated by ChEMBL					Assay Description Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9693-700 (2014) Article DOI: 10.1021/jm4013888 BindingDB Entry DOI: 10.7270/Q21G0NQ1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50444284 (CHEMBL3093637 | US9649309, Compound UNC2084A) Show SMILES CCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(NCC2CCNCC2)n1 Show InChI InChI=1S/C25H37N7O4S/c1-2-3-10-27-25-29-18-22(23(31-25)28-17-19-8-11-26-12-9-19)24(33)30-20-4-6-21(7-5-20)37(34,35)32-13-15-36-16-14-32/h4-7,18-19,26H,2-3,8-17H2,1H3,(H,30,33)(H2,27,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh Curated by ChEMBL					Assay Description Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...				J Med Chem 56: 9693-700 (2014) Article DOI: 10.1021/jm4013888 BindingDB Entry DOI: 10.7270/Q21G0NQ1
					More data for this Ligand-Target Pair