BDBM50444454 CHEMBL3092368

SMILES: CC(=O)Nc1nc(C)c(s1)-c1nc(CCO)no1

InChI Key: InChIKey=QJEIQCZLXODXCV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444454 (CHEMBL3092368) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CCO)no1 Show InChI InChI=1S/C10H12N4O3S/c1-5-8(18-10(11-5)12-6(2)16)9-13-7(3-4-15)14-17-9/h15H,3-4H2,1-2H3,(H,11,12,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair