BDBM50444896 CHEMBL3099634

SMILES: O=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1

InChI Key: InChIKey=VHNMUKVZJGCDSZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome Macropain subunit (Homo sapiens (Human))	BDBM50444896 (CHEMBL3099634) Show SMILES O=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1 Show InChI InChI=1S/C29H40N2O3/c32-29(25-9-13-27(14-10-25)33-23-21-30-17-5-1-2-6-18-30)26-11-15-28(16-12-26)34-24-22-31-19-7-3-4-8-20-31/h9-16H,1-8,17-24H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50444896 (CHEMBL3099634) Show SMILES O=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1 Show InChI InChI=1S/C29H40N2O3/c32-29(25-9-13-27(14-10-25)33-23-21-30-17-5-1-2-6-18-30)26-11-15-28(16-12-26)34-24-22-31-19-7-3-4-8-20-31/h9-16H,1-8,17-24H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50444896 (CHEMBL3099634) Show SMILES O=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1 Show InChI InChI=1S/C29H40N2O3/c32-29(25-9-13-27(14-10-25)33-23-21-30-17-5-1-2-6-18-30)26-11-15-28(16-12-26)34-24-22-31-19-7-3-4-8-20-31/h9-16H,1-8,17-24H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
					More data for this Ligand-Target Pair