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SMILES: Cc1cccc(NC(=O)c2cc(Br)ccc2C(O)=O)n1

InChI Key: InChIKey=IGEMKSYEPSTRAZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50445052   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sortilin


(Homo sapiens (Human))		BDBM50445052
PNG
(CHEMBL3098748)
Show SMILES Cc1cccc(NC(=O)c2cc(Br)ccc2C(O)=O)n1
Show InChI InChI=1S/C14H11BrN2O3/c1-8-3-2-4-12(16-8)17-13(18)11-7-9(15)5-6-10(11)14(19)20/h2-7H,1H3,(H,19,20)(H,16,17,18)
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Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]-neurotensin from sortilin (unknown origin) incubated 30 mins prior to [3H]-neurotensin addition measured after 6 hrs by scintill...

Bioorg Med Chem Lett 24: 177-80 (2013)


Article DOI: 10.1016/j.bmcl.2013.11.046
BindingDB Entry DOI: 10.7270/Q2RN39BB
More data for this
Ligand-Target Pair