null

SMILES: OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)C#Cc1ccccc1

InChI Key: InChIKey=GAGLGFSQMXZPHF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50445577 (CHEMBL3103305) Show SMILES OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)C#Cc1ccccc1 |TLB:0:1:10.8.7:5,9:8:5:3.2.1,1:2:10:7.6.5,1:6:10:3.9.2,17:10:5:3.2.1,11:10:3.9.2:7.6.5,THB:9:2:10.8.7:5,17:10:3.9.2:7.6.5,11:10:5:3.2.1,(45.45,-12.98,;44.16,-13.83,;44.14,-15.35,;42.75,-15.7,;41.43,-15.21,;41.42,-13.73,;42.76,-13.25,;41.72,-14.48,;41.72,-16.07,;43.14,-16.63,;40.23,-16.49,;38.89,-15.69,;37.55,-16.44,;36.06,-16.01,;35.2,-17.29,;36.16,-18.5,;37.6,-17.97,;40.22,-18.02,;40.21,-19.56,;40.2,-21.1,;38.86,-21.86,;38.85,-23.4,;40.18,-24.18,;41.53,-23.41,;41.53,-21.87,)| Show InChI InChI=1S/C20H22N4O/c25-19-14-8-16-10-15(19)11-17(9-14)20(16,12-18-21-23-24-22-18)7-6-13-4-2-1-3-5-13/h1-5,14-17,19,25H,8-12H2,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	737	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 24: 654-60 (2014) Article DOI: 10.1016/j.bmcl.2013.11.066 BindingDB Entry DOI: 10.7270/Q20Z74RF
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50445577 (CHEMBL3103305) Show SMILES OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)C#Cc1ccccc1 |TLB:0:1:10.8.7:5,9:8:5:3.2.1,1:2:10:7.6.5,1:6:10:3.9.2,17:10:5:3.2.1,11:10:3.9.2:7.6.5,THB:9:2:10.8.7:5,17:10:3.9.2:7.6.5,11:10:5:3.2.1,(45.45,-12.98,;44.16,-13.83,;44.14,-15.35,;42.75,-15.7,;41.43,-15.21,;41.42,-13.73,;42.76,-13.25,;41.72,-14.48,;41.72,-16.07,;43.14,-16.63,;40.23,-16.49,;38.89,-15.69,;37.55,-16.44,;36.06,-16.01,;35.2,-17.29,;36.16,-18.5,;37.6,-17.97,;40.22,-18.02,;40.21,-19.56,;40.2,-21.1,;38.86,-21.86,;38.85,-23.4,;40.18,-24.18,;41.53,-23.41,;41.53,-21.87,)| Show InChI InChI=1S/C20H22N4O/c25-19-14-8-16-10-15(19)11-17(9-14)20(16,12-18-21-23-24-22-18)7-6-13-4-2-1-3-5-13/h1-5,14-17,19,25H,8-12H2,(H,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 24: 654-60 (2014) Article DOI: 10.1016/j.bmcl.2013.11.066 BindingDB Entry DOI: 10.7270/Q20Z74RF
					More data for this Ligand-Target Pair