BDBM50446373 CHEMBL3109624

SMILES: Cc1[nH]c2ccccc2c1C(Nc1ccc(C)c(C)c1)c1ccccc1Cl

InChI Key: InChIKey=OHPHITAKOZIRQQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50446373 (CHEMBL3109624) Show SMILES Cc1[nH]c2ccccc2c1C(Nc1ccc(C)c(C)c1)c1ccccc1Cl Show InChI InChI=1S/C24H23ClN2/c1-15-12-13-18(14-16(15)2)27-24(19-8-4-6-10-21(19)25)23-17(3)26-22-11-7-5-9-20(22)23/h4-14,24,26-27H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of LG190178-induced VDR-LBD (unknown origin)-SRC2-3 interaction after 2 hrs by fluorescence polarization assay				ACS Med Chem Lett 5: 199-204 (2014) Article DOI: 10.1021/ml400462j BindingDB Entry DOI: 10.7270/Q2KK9D8Q
					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50446373 (CHEMBL3109624) Show SMILES Cc1[nH]c2ccccc2c1C(Nc1ccc(C)c(C)c1)c1ccccc1Cl Show InChI InChI=1S/C24H23ClN2/c1-15-12-13-18(14-16(15)2)27-24(19-8-4-6-10-21(19)25)23-17(3)26-22-11-7-5-9-20(22)23/h4-14,24,26-27H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Inhibition of 1,25(OH)2D3-induced VDR (unknown origin)-mediated CYP24A1 transcription expressed in HEK293T cells after 16 hrs by luciferase reporter ...				ACS Med Chem Lett 5: 199-204 (2014) Article DOI: 10.1021/ml400462j BindingDB Entry DOI: 10.7270/Q2KK9D8Q
					More data for this Ligand-Target Pair