BDBM50446766 CHEMBL3114597

SMILES: FC(F)(F)c1ccc(OC2CCN(CC2)C(=O)N[C@H]2C[C@@H]2c2ccccc2)cc1

InChI Key: InChIKey=QEGWVLIYGKYYLC-UXHICEINSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50446766 (CHEMBL3114597) Show SMILES FC(F)(F)c1ccc(OC2CCN(CC2)C(=O)N[C@H]2C[C@@H]2c2ccccc2)cc1 |r| Show InChI InChI=1S/C22H23F3N2O2/c23-22(24,25)16-6-8-17(9-7-16)29-18-10-12-27(13-11-18)21(28)26-20-14-19(20)15-4-2-1-3-5-15/h1-9,18-20H,10-14H2,(H,26,28)/t19-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assay				Bioorg Med Chem 22: 1548-57 (2014) Article DOI: 10.1016/j.bmc.2014.01.040 BindingDB Entry DOI: 10.7270/Q22F7PW9
					More data for this Ligand-Target Pair
Epoxide hydrolase 2 (Rattus norvegicus)	BDBM50446766 (CHEMBL3114597) Show SMILES FC(F)(F)c1ccc(OC2CCN(CC2)C(=O)N[C@H]2C[C@@H]2c2ccccc2)cc1 |r| Show InChI InChI=1S/C22H23F3N2O2/c23-22(24,25)16-6-8-17(9-7-16)29-18-10-12-27(13-11-18)21(28)26-20-14-19(20)15-4-2-1-3-5-15/h1-9,18-20H,10-14H2,(H,26,28)/t19-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assay				Bioorg Med Chem 22: 1548-57 (2014) Article DOI: 10.1016/j.bmc.2014.01.040 BindingDB Entry DOI: 10.7270/Q22F7PW9
					More data for this Ligand-Target Pair