BDBM50446823 CHEMBL3115054

SMILES: OC(=O)[C@@H]1Cc2ccc(OC\C=C\COc3ccc(Cl)c(c3)C(=O)N1)nc2

InChI Key: InChIKey=FWOZSFGPVXYBNW-PYKQWIPUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha2/beta1 (Homo sapiens (Human))	BDBM50446823 (CHEMBL3115054) Show SMILES OC(=O)[C@@H]1Cc2ccc(OC\C=C\COc3ccc(Cl)c(c3)C(=O)N1)nc2 |r,t:11| Show InChI InChI=1S/C19H17ClN2O5/c20-15-5-4-13-10-14(15)18(23)22-16(19(24)25)9-12-3-6-17(21-11-12)27-8-2-1-7-26-13/h1-6,10-11,16H,7-9H2,(H,22,23)(H,24,25)/b2-1+/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	134	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi R&D Curated by ChEMBL					Assay Description Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...				ACS Med Chem Lett 5: 193-8 (2014) Article DOI: 10.1021/ml4004556 BindingDB Entry DOI: 10.7270/Q2P84DDF
					More data for this Ligand-Target Pair