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SMILES: Fc1cc(cc(c1)[C@](Cc1ccccc1)(Nc1nc2CCCCc2s1)c1ccc(Cl)cn1)C(F)(F)F

InChI Key: InChIKey=PQVJKJVNAQMFDJ-SANMLTNESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447543   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50447543
PNG
(CHEMBL3116343)
Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(Nc1nc2CCCCc2s1)c1ccc(Cl)cn1)C(F)(F)F |r|
Show InChI InChI=1S/C27H22ClF4N3S/c28-20-10-11-24(33-16-20)26(15-17-6-2-1-3-7-17,18-12-19(27(30,31)32)14-21(29)13-18)35-25-34-22-8-4-5-9-23(22)36-25/h1-3,6-7,10-14,16H,4-5,8-9,15H2,(H,34,35)/t26-/m0/s1
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Article
PubMed
n/an/a 1.08E+4n/an/an/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CETP using [3H]-CE/HDL by scintillation proximity assay

Bioorg Med Chem Lett 24: 860-4 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.088
BindingDB Entry DOI: 10.7270/Q2WM1FW9
More data for this
Ligand-Target Pair