BDBM50447916 CHEMBL3114987

SMILES: Cc1c([nH]n(-c2nc3ccccc3[nH]2)c1=O)-c1ccccc1

InChI Key: InChIKey=QMSKOZRAQNKEPN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Homo sapiens (Human))	BDBM50447916 (CHEMBL3114987) Show SMILES Cc1c([nH]n(-c2nc3ccccc3[nH]2)c1=O)-c1ccccc1 Show InChI InChI=1S/C17H14N4O/c1-11-15(12-7-3-2-4-8-12)20-21(16(11)22)17-18-13-9-5-6-10-14(13)19-17/h2-10,20H,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hyogo University of Health Science Curated by ChEMBL					Assay Description Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis				Bioorg Med Chem Lett 24: 1071-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.008 BindingDB Entry DOI: 10.7270/Q2FF3TVD
					More data for this Ligand-Target Pair