BDBM50448181 CHEMBL3120561

SMILES: COc1ccccc1NC(=S)Nc1cccc(Cl)c1

InChI Key: InChIKey=ZDJXIKDBZWYIFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50448181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50448181 (CHEMBL3120561) Show SMILES COc1ccccc1NC(=S)Nc1cccc(Cl)c1 Show InChI InChI=1S/C14H13ClN2OS/c1-18-13-8-3-2-7-12(13)17-14(19)16-11-6-4-5-10(15)9-11/h2-9H,1H3,(H2,16,17,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University Karachi Curated by ChEMBL					Assay Description Inhibition of jack bean urease using urea as substrate assessed as ammonia production after 15 mins by indophenol method				Eur J Med Chem 74: 314-23 (2014) Article DOI: 10.1016/j.ejmech.2014.01.001 BindingDB Entry DOI: 10.7270/Q2VH5QBM
					More data for this Ligand-Target Pair