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SMILES: O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)[C@@H]1C[C@H]1c1cccnc1

InChI Key: InChIKey=QHMWQTJEUKVYBF-XZOQPEGZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50448632   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))		BDBM50448632
PNG
(CHEMBL3127497)
Show SMILES O=C(NCCCCC1CCN(CC1)C(=O)c1ccccc1)[C@@H]1C[C@H]1c1cccnc1 |r|
Show InChI InChI=1S/C25H31N3O2/c29-24(23-17-22(23)21-10-6-13-26-18-21)27-14-5-4-7-19-11-15-28(16-12-19)25(30)20-8-2-1-3-9-20/h1-3,6,8-10,13,18-19,22-23H,4-5,7,11-12,14-17H2,(H,27,29)/t22-,23+/m0/s1
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MMDB

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PC cid
PC sid
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Article
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n/an/a 4.70n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His-tagged human full-length NAMPT expressed in Escherichia coli Rosetta DE3 using nicotinamide as substrate preincubated fo...

J Med Chem 57: 770-92 (2014)


Article DOI: 10.1021/jm4015108
BindingDB Entry DOI: 10.7270/Q2BC412B
More data for this
Ligand-Target Pair