BDBM50451068 CHEMBL4204620

SMILES: Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccccn2)CC1)c1ccccc1

InChI Key: InChIKey=FOPSPSAWXABOGD-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50451068 (CHEMBL4204620) Show SMILES Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccccn2)CC1)c1ccccc1 Show InChI InChI=1S/C25H27ClN4O.ClH/c26-22-11-9-21(10-12-22)24(20-6-2-1-3-7-20)30-18-16-29(17-19-30)15-14-28-25(31)23-8-4-5-13-27-23;/h1-13,24H,14-19H2,(H,28,31);1H	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli "Federico II" Via D. Montesano Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from serotonin 5-HT2C receptor in Sprague-Dawley rat brain cortex homogenates incubated for 15 mins by liquid scintil...				Bioorg Med Chem 25: 5820-5837 (2017) Article DOI: 10.1016/j.bmc.2017.09.018 BindingDB Entry DOI: 10.7270/Q2VD721F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50451068 (CHEMBL4204620) Show SMILES Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccccn2)CC1)c1ccccc1 Show InChI InChI=1S/C25H27ClN4O.ClH/c26-22-11-9-21(10-12-22)24(20-6-2-1-3-7-20)30-18-16-29(17-19-30)15-14-28-25(31)23-8-4-5-13-27-23;/h1-13,24H,14-19H2,(H,28,31);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	504	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli "Federico II" Via D. Montesano Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from serotonin 5-HT2A receptor in Sprague-Dawley rat brain cortex homogenates incubated for 15 mins by liquid scintill...				Bioorg Med Chem 25: 5820-5837 (2017) Article DOI: 10.1016/j.bmc.2017.09.018 BindingDB Entry DOI: 10.7270/Q2VD721F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50451068 (CHEMBL4204620) Show SMILES Cl.Clc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccccn2)CC1)c1ccccc1 Show InChI InChI=1S/C25H27ClN4O.ClH/c26-22-11-9-21(10-12-22)24(20-6-2-1-3-7-20)30-18-16-29(17-19-30)15-14-28-25(31)23-8-4-5-13-27-23;/h1-13,24H,14-19H2,(H,28,31);1H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Farmacia Universit£ di Napoli "Federico II" Via D. Montesano Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from serotonin 5-HT1A receptor in Sprague-Dawley rat brain cortex homogenates incubated for 30 mins by liquid scintill...				Bioorg Med Chem 25: 5820-5837 (2017) Article DOI: 10.1016/j.bmc.2017.09.018 BindingDB Entry DOI: 10.7270/Q2VD721F
					More data for this Ligand-Target Pair