BDBM50451591 CHEMBL4208387

SMILES: CCOc1cccc(\C=N\NC(=O)CN[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c1O

InChI Key: InChIKey=VGMCIAYHZHFPDM-BJPPMWOHSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50451591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50451591 (CHEMBL4208387) Show SMILES CCOc1cccc(\C=N\NC(=O)CN[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c1O |r| Show InChI InChI=1S/C20H21F2N3O3/c1-2-28-18-5-3-4-13(20(18)27)10-24-25-19(26)11-23-17-9-14(17)12-6-7-15(21)16(22)8-12/h3-8,10,14,17,23,27H,2,9,11H2,1H3,(H,25,26)/b24-10+/t14-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Zhengzhou University Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 27: 5036-5039 (2017) Article DOI: 10.1016/j.bmcl.2017.10.003 BindingDB Entry DOI: 10.7270/Q2J105QD
					More data for this Ligand-Target Pair