BDBM50452208 CHEMBL4215607

SMILES: Cn1ncc2c(nc(Cl)nc12)N1CCCC1c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=RZPRIARPGSKPQC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50452208 (CHEMBL4215607) Show SMILES Cn1ncc2c(nc(Cl)nc12)N1CCCC1c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H15ClF3N5/c1-25-14-12(9-22-25)15(24-16(18)23-14)26-8-2-3-13(26)10-4-6-11(7-5-10)17(19,20)21/h4-7,9,13H,2-3,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Binding affinity to PDE2 (unknown origin) by SPR analysis				Bioorg Med Chem Lett 27: 5167-5171 (2017) Article DOI: 10.1016/j.bmcl.2017.10.054 BindingDB Entry DOI: 10.7270/Q28C9ZV3
					More data for this Ligand-Target Pair