null

SMILES: OC(=O)C(F)(F)F.COc1ccc(cc1O)-c1c2c(n3ccc4cc(O)c(OC)cc4c13)c(=O)oc1cc(OCCCN(C)C)c(OC)cc21

InChI Key: InChIKey=SNZMPFNYAZMZKW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50452333 (CHEMBL4206193) Show SMILES OC(=O)C(F)(F)F.COc1ccc(cc1O)-c1c2c(n3ccc4cc(O)c(OC)cc4c13)c(=O)oc1cc(OCCCN(C)C)c(OC)cc21 Show InChI InChI=1S/C33H32N2O8/c1-34(2)10-6-12-42-28-17-25-21(16-27(28)41-5)30-29(19-7-8-24(39-3)22(36)14-19)31-20-15-26(40-4)23(37)13-18(20)9-11-35(31)32(30)33(38)43-25/h7-9,11,13-17,36-37H,6,10,12H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Nagasaki University Curated by ChEMBL					Assay Description Inhibition of recombinant EGFR (unknown origin) T790M/L858R double mutant preincubated for 30 mins followed by poly (Glu-Tyr) biotinylated peptide su...				Bioorg Med Chem 25: 6563-6580 (2017) Article DOI: 10.1016/j.bmc.2017.10.030 BindingDB Entry DOI: 10.7270/Q2RB7764
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50452333 (CHEMBL4206193) Show SMILES OC(=O)C(F)(F)F.COc1ccc(cc1O)-c1c2c(n3ccc4cc(O)c(OC)cc4c13)c(=O)oc1cc(OCCCN(C)C)c(OC)cc21 Show InChI InChI=1S/C33H32N2O8/c1-34(2)10-6-12-42-28-17-25-21(16-27(28)41-5)30-29(19-7-8-24(39-3)22(36)14-19)31-20-15-26(40-4)23(37)13-18(20)9-11-35(31)32(30)33(38)43-25/h7-9,11,13-17,36-37H,6,10,12H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	215	n/a	n/a	n/a	n/a	n/a	n/a
Nagasaki University Curated by ChEMBL					Assay Description Inhibition of recombinant wild type EGFR (696 to C-terminal residues) (unknown origin) preincubated for 30 mins followed by poly (Glu-Tyr) biotinylat...				Bioorg Med Chem 25: 6563-6580 (2017) Article DOI: 10.1016/j.bmc.2017.10.030 BindingDB Entry DOI: 10.7270/Q2RB7764
					More data for this Ligand-Target Pair