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SMILES: Clc1ccc(CCN2CCN(CC2)c2nsc3ccccc23)cc1Cl

InChI Key: InChIKey=IWHKEAOARZJLDH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50452370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50452370 (CHEMBL4209430) Show SMILES Clc1ccc(CCN2CCN(CC2)c2nsc3ccccc23)cc1Cl Show InChI InChI=1S/C19H19Cl2N3S/c20-16-6-5-14(13-17(16)21)7-8-23-9-11-24(12-10-23)19-15-3-1-2-4-18(15)25-22-19/h1-6,13H,7-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Pharmaceutical Industry Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation count...				Bioorg Med Chem Lett 27: 5420-5423 (2017) Article DOI: 10.1016/j.bmcl.2017.11.007 BindingDB Entry DOI: 10.7270/Q2GX4F4Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50452370 (CHEMBL4209430) Show SMILES Clc1ccc(CCN2CCN(CC2)c2nsc3ccccc23)cc1Cl Show InChI InChI=1S/C19H19Cl2N3S/c20-16-6-5-14(13-17(16)21)7-8-23-9-11-24(12-10-23)19-15-3-1-2-4-18(15)25-22-19/h1-6,13H,7-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Pharmaceutical Industry Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...				Bioorg Med Chem Lett 27: 5420-5423 (2017) Article DOI: 10.1016/j.bmcl.2017.11.007 BindingDB Entry DOI: 10.7270/Q2GX4F4Z
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50452370 (CHEMBL4209430) Show SMILES Clc1ccc(CCN2CCN(CC2)c2nsc3ccccc23)cc1Cl Show InChI InChI=1S/C19H19Cl2N3S/c20-16-6-5-14(13-17(16)21)7-8-23-9-11-24(12-10-23)19-15-3-1-2-4-18(15)25-22-19/h1-6,13H,7-12H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Pharmaceutical Industry Curated by ChEMBL					Assay Description Inhibition of SERT in rat brain synaptosomes assessed as reduction in [3H]-5-HT uptake measured after 15 mins by scintillation counting method				Bioorg Med Chem Lett 27: 5420-5423 (2017) Article DOI: 10.1016/j.bmcl.2017.11.007 BindingDB Entry DOI: 10.7270/Q2GX4F4Z
					More data for this Ligand-Target Pair