BDBM50452915 CHEMBL4204455

SMILES: CCC(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key: InChIKey=DFWHOCVEAQNIBM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50452915 (CHEMBL4204455) Show SMILES CCC(=O)N1CCN(Cc2ccc(F)cc2)CC1 Show InChI InChI=1S/C14H19FN2O/c1-2-14(18)17-9-7-16(8-10-17)11-12-3-5-13(15)6-4-12/h3-6H,2,7-11H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit� di Messina Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate preincubated with substrate for 10 mins followed by protein addition...				J Med Chem 61: 3908-3917 (2018) Article DOI: 10.1021/acs.jmedchem.7b01745 BindingDB Entry DOI: 10.7270/Q2V127DR
					More data for this Ligand-Target Pair