BDBM50452921 CHEMBL4212134

SMILES: Cc1cccc(c1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key: InChIKey=URNRWBXPUIHPJR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50452921 (CHEMBL4212134) Show SMILES Cc1cccc(c1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1 Show InChI InChI=1S/C19H21FN2O/c1-15-3-2-4-17(13-15)19(23)22-11-9-21(10-12-22)14-16-5-7-18(20)8-6-16/h2-8,13H,9-12,14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit� di Messina Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate preincubated with substrate for 10 mins followed by protein addition...				J Med Chem 61: 3908-3917 (2018) Article DOI: 10.1021/acs.jmedchem.7b01745 BindingDB Entry DOI: 10.7270/Q2V127DR
					More data for this Ligand-Target Pair