BDBM50453571 CHEMBL171054

SMILES: CC(COC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O)Cc1ccccc1

InChI Key: InChIKey=XDSOEMVFZXXLNT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453571   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50453571 (CHEMBL171054) Show SMILES CC(COC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O)Cc1ccccc1 Show InChI InChI=1S/C24H25NO5/c1-16(11-17-5-3-2-4-6-17)15-30-24(29)21-13-19(7-9-23(21)28)25-14-18-12-20(26)8-10-22(18)27/h2-10,12-13,16,25-28H,11,14-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
U266 INSERM-URA D1500 CNRS Curated by ChEMBL					Assay Description Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cells				J Med Chem 37: 845-59 (1994) BindingDB Entry DOI: 10.7270/Q2QV3KJ3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50453571 (CHEMBL171054) Show SMILES CC(COC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O)Cc1ccccc1 Show InChI InChI=1S/C24H25NO5/c1-16(11-17-5-3-2-4-6-17)15-30-24(29)21-13-19(7-9-23(21)28)25-14-18-12-20(26)8-10-22(18)27/h2-10,12-13,16,25-28H,11,14-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
U266 INSERM-URA D1500 CNRS Curated by ChEMBL					Assay Description Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membrane				J Med Chem 37: 845-59 (1994) BindingDB Entry DOI: 10.7270/Q2QV3KJ3
					More data for this Ligand-Target Pair