null

SMILES: Oc1ccc(O)c(CNc2ccc(O)c(CC(=O)NOCc3ccccc3)c2)c1

InChI Key: InChIKey=NYVYOBPBOHULAP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50453589 (CHEMBL352589) Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(CC(=O)NOCc3ccccc3)c2)c1 Show InChI InChI=1S/C22H22N2O5/c25-19-7-9-21(27)17(11-19)13-23-18-6-8-20(26)16(10-18)12-22(28)24-29-14-15-4-2-1-3-5-15/h1-11,23,25-27H,12-14H2,(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
U266 INSERM-URA D1500 CNRS Curated by ChEMBL					Assay Description Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membrane				J Med Chem 37: 845-59 (1994) BindingDB Entry DOI: 10.7270/Q2QV3KJ3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50453589 (CHEMBL352589) Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(CC(=O)NOCc3ccccc3)c2)c1 Show InChI InChI=1S/C22H22N2O5/c25-19-7-9-21(27)17(11-19)13-23-18-6-8-20(26)16(10-18)12-22(28)24-29-14-15-4-2-1-3-5-15/h1-11,23,25-27H,12-14H2,(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
U266 INSERM-URA D1500 CNRS Curated by ChEMBL					Assay Description Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cells				J Med Chem 37: 845-59 (1994) BindingDB Entry DOI: 10.7270/Q2QV3KJ3
					More data for this Ligand-Target Pair