BDBM50453926 CHEMBL4213979
SMILES: Cl.FCCOc1cccc(CCN2CCC(CCc3ccccc3)CC2)c1
InChI Key: InChIKey=BNEKRHSJWOARGT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Synaptic vesicular amine transporter (Rattus norvegicus (Rat)) | BDBM50453926 (CHEMBL4213979) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine uptake at VMAT2 in rat striatal synaptic vesicles by scintillation spectrometry | Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50453926 (CHEMBL4213979) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Inhibition of [3H]serotonin uptake at SERT in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measured after 10 mi... | Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50453926 (CHEMBL4213979) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine uptake at dopamine transporter in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measu... | Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae) | BDBM50453926 (CHEMBL4213979) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky Curated by ChEMBL | Assay Description Displacement of [3H]Dofetilide from human ERG expressed in HEK293 cells after 60 mins by scintillation spectrometry | Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5 | |||||||||||
More data for this Ligand-Target Pair |