BDBM50453933 CHEMBL4210865

SMILES: Cl.FCCOc1ccccc1CCC1CCN(CCc2ccccc2Cl)CC1

InChI Key: InChIKey=TVFJERMAGQWXNA-UHFFFAOYSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50453933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50453933 (CHEMBL4210865) Show SMILES Cl.FCCOc1ccccc1CCC1CCN(CCc2ccccc2Cl)CC1 Show InChI InChI=1S/C23H29ClFNO/c24-22-7-3-1-5-20(22)13-17-26-15-11-19(12-16-26)9-10-21-6-2-4-8-23(21)27-18-14-25/h1-8,19H,9-18H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at VMAT2 in rat striatal synaptic vesicles by scintillation spectrometry				Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50453933 (CHEMBL4210865) Show SMILES Cl.FCCOc1ccccc1CCC1CCN(CCc2ccccc2Cl)CC1 Show InChI InChI=1S/C23H29ClFNO/c24-22-7-3-1-5-20(22)13-17-26-15-11-19(12-16-26)9-10-21-6-2-4-8-23(21)27-18-14-25/h1-8,19H,9-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]serotonin uptake at SERT in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measured after 10 mi...				Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50453933 (CHEMBL4210865) Show SMILES Cl.FCCOc1ccccc1CCC1CCN(CCc2ccccc2Cl)CC1 Show InChI InChI=1S/C23H29ClFNO/c24-22-7-3-1-5-20(22)13-17-26-15-11-19(12-16-26)9-10-21-6-2-4-8-23(21)27-18-14-25/h1-8,19H,9-18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at dopamine transporter in rat striatal synaptosomes preincubated for 5 mins followed by radioligand addition measu...				Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5
					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50453933 (CHEMBL4210865) Show SMILES Cl.FCCOc1ccccc1CCC1CCN(CCc2ccccc2Cl)CC1 Show InChI InChI=1S/C23H29ClFNO/c24-22-7-3-1-5-20(22)13-17-26-15-11-19(12-16-26)9-10-21-6-2-4-8-23(21)27-18-14-25/h1-8,19H,9-18H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]Dofetilide from human ERG expressed in HEK293 cells after 60 mins by scintillation spectrometry				Bioorg Med Chem Lett 27: 5467-5472 (2017) Article DOI: 10.1016/j.bmcl.2017.10.039 BindingDB Entry DOI: 10.7270/Q2BP05B5
					More data for this Ligand-Target Pair