BDBM50454317 CHEMBL4203265

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=[#6])-[#6](-[#8])-[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c2c1oc1ccc(-[#8])cc1c2=O

InChI Key: InChIKey=ITBYKCNYFABTPS-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50454317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable maltase-glucoamylase 2 (Homo sapiens)	BDBM50454317 (CHEMBL4203265) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=[#6])-[#6](-[#8])-[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c2c1oc1ccc(-[#8])cc1c2=O Show InChI InChI=1S/C28H32O6/c1-15(2)7-6-8-17(5)22(30)14-21-25(31)19(11-9-16(3)4)26(32)24-27(33)20-13-18(29)10-12-23(20)34-28(21)24/h7,9-10,12-13,22,29-32H,5-6,8,11,14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysis				Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50454317 (CHEMBL4203265) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=[#6])-[#6](-[#8])-[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c2c1oc1ccc(-[#8])cc1c2=O Show InChI InChI=1S/C28H32O6/c1-15(2)7-6-8-17(5)22(30)14-21-25(31)19(11-9-16(3)4)26(32)24-27(33)20-13-18(29)10-12-23(20)34-28(21)24/h7,9-10,12-13,22,29-32H,5-6,8,11,14H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysis				Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50454317 (CHEMBL4203265) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=[#6])-[#6](-[#8])-[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c2c1oc1ccc(-[#8])cc1c2=O Show InChI InChI=1S/C28H32O6/c1-15(2)7-6-8-17(5)22(30)14-21-25(31)19(11-9-16(3)4)26(32)24-27(33)20-13-18(29)10-12-23(20)34-28(21)24/h7,9-10,12-13,22,29-32H,5-6,8,11,14H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by spectrophotometry				Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34
					More data for this Ligand-Target Pair
Probable maltase-glucoamylase 2 (Homo sapiens)	BDBM50454317 (CHEMBL4203265) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=[#6])-[#6](-[#8])-[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c2c1oc1ccc(-[#8])cc1c2=O Show InChI InChI=1S/C28H32O6/c1-15(2)7-6-8-17(5)22(30)14-21-25(31)19(11-9-16(3)4)26(32)24-27(33)20-13-18(29)10-12-23(20)34-28(21)24/h7,9-10,12-13,22,29-32H,5-6,8,11,14H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate measured for 15 mins by spectrophotometry				Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34
					More data for this Ligand-Target Pair