null
SMILES: COc1c(O)ccc2c1oc1c3c(OC(CO)C3(C)C)cc(O)c1c2=O
InChI Key: InChIKey=DGPPUQGDNLFZCD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50454322 (CHEMBL4218731) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by Dixon plot analysis | Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable maltase-glucoamylase 2 (Homo sapiens) | BDBM50454322 (CHEMBL4218731) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate by Dixon plot analysis | Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50454322 (CHEMBL4218731) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using P-NPP as substrate after 10 mins by spectrophotometry | Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable maltase-glucoamylase 2 (Homo sapiens) | BDBM50454322 (CHEMBL4218731) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of alpha-glucosidase (unknown origin) using PNP-G as substrate measured for 15 mins by spectrophotometry | Bioorg Med Chem 26: 737-746 (2018) Article DOI: 10.1016/j.bmc.2017.12.043 BindingDB Entry DOI: 10.7270/Q2CJ8H34 | |||||||||||
More data for this Ligand-Target Pair |