BDBM50454413 CHEMBL334944

SMILES: CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)N(C)OCc1ccccc1)C(C)C)C(=O)N[C@@H](CO)C(O)=O

InChI Key: InChIKey=GWMOBEQQAAMCPO-XWUOBKMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50454413 (CHEMBL334944) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)N(C)OCc1ccccc1)C(C)C)C(=O)N[C@@H](CO)C(O)=O Show InChI InChI=1S/C26H41N5O8/c1-15(2)11-19(24(35)29-20(13-32)26(37)38)28-25(36)22(16(3)4)30-23(34)18(27)12-21(33)31(5)39-14-17-9-7-6-8-10-17/h6-10,15-16,18-20,22,32H,11-14,27H2,1-5H3,(H,28,36)(H,29,35)(H,30,34)(H,37,38)/t18-,19-,20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vivo activity against Protein farnesyltransferase				J Med Chem 39: 4197-210 (1996) Article DOI: 10.1021/jm960190h BindingDB Entry DOI: 10.7270/Q2WS8VRV
					More data for this Ligand-Target Pair