BDBM50454420 CHEMBL2112708

SMILES: [#6]-[#16]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7](-[#8])-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6](-[#6])-[#6])-[#6](-[#6])-[#6])-[#6](-[#8])=O

InChI Key: InChIKey=VDXARTSSWJMJKI-KWCOWBTJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50454420 (CHEMBL2112708) Show SMILES [#6]-[#16]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6]-[#6](=O)-[#7](-[#8])-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6](-[#6])-[#6])-[#6](-[#6])-[#6])-[#6](-[#8])=O Show InChI InChI=1S/C33H56N4O7S/c1-21(2)12-10-13-24(7)14-11-15-25(8)16-18-37(44)28(39)20-27(38)35-29(22(3)4)32(41)36-30(23(5)6)31(40)34-26(33(42)43)17-19-45-9/h12,14,16,22-23,26,29-30,44H,10-11,13,15,17-20H2,1-9H3,(H,34,40)(H,35,38)(H,36,41)(H,42,43)/b24-14+,25-16+/t26-,29-,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vivo activity against Protein farnesyltransferase				J Med Chem 39: 4197-210 (1996) Article DOI: 10.1021/jm960190h BindingDB Entry DOI: 10.7270/Q2WS8VRV
					More data for this Ligand-Target Pair