BDBM50454948 CHEMBL311285

SMILES: Cc1cc(C)c(NC(=O)N(Cc2cccc(c2)-n2cccc2)C2CCCCCC2)c(C)c1

InChI Key: InChIKey=JKRAEHLAXRQUIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50454948 (CHEMBL311285) Show SMILES Cc1cc(C)c(NC(=O)N(Cc2cccc(c2)-n2cccc2)C2CCCCCC2)c(C)c1 Show InChI InChI=1S/C28H35N3O/c1-21-17-22(2)27(23(3)18-21)29-28(32)31(25-12-6-4-5-7-13-25)20-24-11-10-14-26(19-24)30-15-8-9-16-30/h8-11,14-19,25H,4-7,12-13,20H2,1-3H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes				J Med Chem 41: 2390-410 (1998) Article DOI: 10.1021/jm9800853 BindingDB Entry DOI: 10.7270/Q2MW2G7V
					More data for this Ligand-Target Pair