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SMILES: Fc1cc(F)c(NC(=O)N(Cc2ccc(cc2)-n2cccc2)C2CCCCCC2)c(F)c1

InChI Key: InChIKey=SFQNEDKFLSSTOV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454950   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50454950
PNG
(CHEMBL80973)
Show SMILES Fc1cc(F)c(NC(=O)N(Cc2ccc(cc2)-n2cccc2)C2CCCCCC2)c(F)c1
Show InChI InChI=1S/C25H26F3N3O/c26-19-15-22(27)24(23(28)16-19)29-25(32)31(21-7-3-1-2-4-8-21)17-18-9-11-20(12-10-18)30-13-5-6-14-30/h5-6,9-16,21H,1-4,7-8,17H2,(H,29,32)
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n/an/a 27n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes

J Med Chem 41: 2390-410 (1998)


Article DOI: 10.1021/jm9800853
BindingDB Entry DOI: 10.7270/Q2MW2G7V
More data for this
Ligand-Target Pair