BDBM50454955 CHEMBL310523

SMILES: Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-n2ccnn2)C2CCCCCC2)c(C)c1

InChI Key: InChIKey=BCSOAOKLWFTXGN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50454955 (CHEMBL310523) Show SMILES Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-n2ccnn2)C2CCCCCC2)c(C)c1 Show InChI InChI=1S/C26H33N5O/c1-19-16-20(2)25(21(3)17-19)28-26(32)30(23-8-6-4-5-7-9-23)18-22-10-12-24(13-11-22)31-15-14-27-29-31/h10-17,23H,4-9,18H2,1-3H3,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes				J Med Chem 41: 2390-410 (1998) Article DOI: 10.1021/jm9800853 BindingDB Entry DOI: 10.7270/Q2MW2G7V
					More data for this Ligand-Target Pair