BindingDB logo
myBDB logout

null

SMILES: Fc1cc(F)c(NC(=O)N(Cc2ccc(cc2)-c2cccs2)C2CCCCCC2)c(F)c1

InChI Key: InChIKey=QOHNXNTVDSJSLO-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454962   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50454962
PNG
(CHEMBL311524)
Show SMILES Fc1cc(F)c(NC(=O)N(Cc2ccc(cc2)-c2cccs2)C2CCCCCC2)c(F)c1
Show InChI InChI=1S/C25H25F3N2OS/c26-19-14-21(27)24(22(28)15-19)29-25(31)30(20-6-3-1-2-4-7-20)16-17-9-11-18(12-10-17)23-8-5-13-32-23/h5,8-15,20H,1-4,6-7,16H2,(H,29,31)
PDB

Reactome pathway
KEGG

UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes

J Med Chem 41: 2390-410 (1998)


Article DOI: 10.1021/jm9800853
BindingDB Entry DOI: 10.7270/Q2MW2G7V
More data for this
Ligand-Target Pair