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SMILES: Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-n2cncn2)C2CCCCCC2)c(C)c1

InChI Key: InChIKey=LWUFZGZUOIDQDZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454966   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50454966
PNG
(CHEMBL78425)
Show SMILES Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-n2cncn2)C2CCCCCC2)c(C)c1
Show InChI InChI=1S/C26H33N5O/c1-19-14-20(2)25(21(3)15-19)29-26(32)30(23-8-6-4-5-7-9-23)16-22-10-12-24(13-11-22)31-18-27-17-28-31/h10-15,17-18,23H,4-9,16H2,1-3H3,(H,29,32)
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PC cid
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Article
PubMed
n/an/a 26n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes

J Med Chem 41: 2390-410 (1998)


Article DOI: 10.1021/jm9800853
BindingDB Entry DOI: 10.7270/Q2MW2G7V
More data for this
Ligand-Target Pair