BDBM50454973 CHEMBL310159

SMILES: Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-n2cccc2)C2CCCCCC2)c(C)c1

InChI Key: InChIKey=MRSQHXGNWFPSII-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50454973 (CHEMBL310159) Show SMILES Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-n2cccc2)C2CCCCCC2)c(C)c1 Show InChI InChI=1S/C28H35N3O/c1-21-18-22(2)27(23(3)19-21)29-28(32)31(26-10-6-4-5-7-11-26)20-24-12-14-25(15-13-24)30-16-8-9-17-30/h8-9,12-19,26H,4-7,10-11,20H2,1-3H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes				J Med Chem 41: 2390-410 (1998) Article DOI: 10.1021/jm9800853 BindingDB Entry DOI: 10.7270/Q2MW2G7V
					More data for this Ligand-Target Pair