BDBM50454989 CHEMBL78597

SMILES: Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-c2cnn(C)c2)C2CCCCCC2)c(C)c1

InChI Key: InChIKey=YZHVDVMPAFWSQJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50454989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50454989 (CHEMBL78597) Show SMILES Cc1cc(C)c(NC(=O)N(Cc2ccc(cc2)-c2cnn(C)c2)C2CCCCCC2)c(C)c1 Show InChI InChI=1S/C28H36N4O/c1-20-15-21(2)27(22(3)16-20)30-28(33)32(26-9-7-5-6-8-10-26)18-23-11-13-24(14-12-23)25-17-29-31(4)19-25/h11-17,19,26H,5-10,18H2,1-4H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes				J Med Chem 41: 2390-410 (1998) Article DOI: 10.1021/jm9800853 BindingDB Entry DOI: 10.7270/Q2MW2G7V
					More data for this Ligand-Target Pair