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null

SMILES: FC(F)(F)c1nc(no1)-c1ccc(cc1)N1[C@@H](CCCC1=O)c1nc2ccccc2s1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 504553
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM504553 ((S)-6-(Benzo[d]thiazol-2-yl)-1-(4-(5-(trifluoromet...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DN485Z
TBA					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM504553 ((S)-6-(Benzo[d]thiazol-2-yl)-1-(4-(5-(trifluoromet...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HDAC8 reagents: HDAC8 was purchased from Enzo Life Sciences [catalog #BML-SE145]. Assays were performed with buffer containing 20 mM HEPES, pH 8.0 [B...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DN485Z
TBA					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM504553 ((S)-6-(Benzo[d]thiazol-2-yl)-1-(4-(5-(trifluoromet...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DN485Z
TBA					More data for this Ligand-Target Pair