BDBM50455587 CHEMBL4205851

SMILES: NCc1ccc(cc1)-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12

InChI Key: InChIKey=DFWSFSFNBJWHKD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C iota type/zeta type (Homo sapiens (Human))	BDBM50455587 (CHEMBL4205851) Show SMILES NCc1ccc(cc1)-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C21H17N5/c22-12-14-1-4-16(5-2-14)26-13-25-19-6-3-15(11-20(19)26)17-7-9-23-21-18(17)8-10-24-21/h1-11,13H,12,22H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Agency for Science, Technology and Research (A*STAR) Curated by ChEMBL					Assay Description Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...				J Med Chem 61: 4386-4396 (2018) Article DOI: 10.1021/acs.jmedchem.8b00060 BindingDB Entry DOI: 10.7270/Q2V69N5Z
					More data for this Ligand-Target Pair