BDBM50455950 CHEMBL4206713

SMILES: [H][C@]12CN(Cc3cccc(C)c3)C[C@@]1(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]([H])(C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@]1([H])C2

InChI Key: InChIKey=OUEYGLPUUWNHEZ-MIWRREBKSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50455950 (CHEMBL4206713) Show SMILES [H][C@]12CN(Cc3cccc(C)c3)C[C@@]1(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]([H])(C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@]1([H])C2 |r,c:36,t:32| Show InChI InChI=1S/C31H37F2NO4/c1-18-5-4-6-19(9-18)14-34-15-20-10-22-23-12-25(32)24-11-21(36)7-8-28(24,2)31(23,33)26(37)13-29(22,3)30(20,17-34)27(38)16-35/h4-9,11,20,22-23,25-26,35,37H,10,12-17H2,1-3H3/t20-,22-,23-,25-,26-,28-,29-,30+,31-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in insect cells after 24 hrs by scintillation proximity as...				J Med Chem 61: 4757-4773 (2018) Article DOI: 10.1021/acs.jmedchem.7b01873 BindingDB Entry DOI: 10.7270/Q2JS9T19
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50455950 (CHEMBL4206713) Show SMILES [H][C@]12CN(Cc3cccc(C)c3)C[C@@]1(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]([H])(C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@]1([H])C2 |r,c:36,t:32| Show InChI InChI=1S/C31H37F2NO4/c1-18-5-4-6-19(9-18)14-34-15-20-10-22-23-12-25(32)24-11-21(36)7-8-28(24,2)31(23,33)26(37)13-29(22,3)30(20,17-34)27(38)16-35/h4-9,11,20,22-23,25-26,35,37H,10,12-17H2,1-3H3/t20-,22-,23-,25-,26-,28-,29-,30+,31-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Induction of nuclear translocation of human recombinant ProLabel-tagged glucocorticoid receptor expressed in CHO-K1 cells after 3 hrs by luminescence...				J Med Chem 61: 4757-4773 (2018) Article DOI: 10.1021/acs.jmedchem.7b01873 BindingDB Entry DOI: 10.7270/Q2JS9T19
					More data for this Ligand-Target Pair