BDBM50456455 CHEMBL4204060

SMILES: CN1C(=O)C(=NN(c2ccccc2)c2ccccc2)c2ccccc12

InChI Key: InChIKey=GBHDVBKJGALDHX-LSDHQDQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50456455 (CHEMBL4204060) Show SMILES CN1C(=O)C(=NN(c2ccccc2)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C21H17N3O/c1-23-19-15-9-8-14-18(19)20(21(23)25)22-24(16-10-4-2-5-11-16)17-12-6-3-7-13-17/h2-15H,1H3/b22-20+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas-CSIC Curated by ChEMBL					Assay Description Inhibition of recombinant catalytic human GST-tagged LLRK2 (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as substr...				Eur J Med Chem 138: 328-342 (2017) Article DOI: 10.1016/j.ejmech.2017.06.060 BindingDB Entry DOI: 10.7270/Q2V40XTP
					More data for this Ligand-Target Pair