BDBM50456456 CHEMBL4208935

SMILES: O=C1N(Cc2ccccc2)c2ccccc2C1=NN(c1ccccc1)c1ccccc1

InChI Key: InChIKey=VEYPYXVQKRCCJE-BYCLXTJYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2) (Homo sapiens (Human))	BDBM50456456 (CHEMBL4208935) Show SMILES O=C1N(Cc2ccccc2)c2ccccc2C1=NN(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H21N3O/c31-27-26(28-30(22-14-6-2-7-15-22)23-16-8-3-9-17-23)24-18-10-11-19-25(24)29(27)20-21-12-4-1-5-13-21/h1-19H,20H2/b28-26+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas-CSIC Curated by ChEMBL					Assay Description Inhibition of recombinant catalytic human GST-tagged LLRK2 (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as substr...				Eur J Med Chem 138: 328-342 (2017) Article DOI: 10.1016/j.ejmech.2017.06.060 BindingDB Entry DOI: 10.7270/Q2V40XTP
					More data for this Ligand-Target Pair