BDBM50456540 CHEMBL4205537

SMILES: Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccccc1F

InChI Key: InChIKey=ZCXHINICKDACIY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50456540 (CHEMBL4205537) Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccccc1F Show InChI InChI=1S/C19H16FNO5S2/c1-12-17(27-19(21-12)15-4-2-3-5-16(15)20)10-26-13-6-8-14(9-7-13)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay				Eur J Med Chem 138: 458-479 (2017) Article DOI: 10.1016/j.ejmech.2017.07.001 BindingDB Entry DOI: 10.7270/Q269765Z
					More data for this Ligand-Target Pair