BDBM50456757 CHEMBL4209008

SMILES: [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)c1ccc(cc1)C#N)C(=O)OC

InChI Key: InChIKey=YAEZMIRHJORXGA-RXLVGJJOSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50456757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50456757 (CHEMBL4209008) Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)c1ccc(cc1)C#N)C(=O)OC |r,c:32,t:15| Show InChI InChI=1S/C38H49NO3/c1-33(2)17-19-38(32(41)42-8)20-18-36(6)27(28(38)22-33)13-14-30-35(5)21-26(25-11-9-24(23-39)10-12-25)31(40)34(3,4)29(35)15-16-37(30,36)7/h9-13,21,28-30H,14-20,22H2,1-8H3/t28-,29-,30+,35-,36+,37+,38-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assay				J Nat Prod 80: 2276-2283 (2017) Article DOI: 10.1021/acs.jnatprod.7b00271 BindingDB Entry DOI: 10.7270/Q2VX0K32
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50456757 (CHEMBL4209008) Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)c1ccc(cc1)C#N)C(=O)OC |r,c:32,t:15| Show InChI InChI=1S/C38H49NO3/c1-33(2)17-19-38(32(41)42-8)20-18-36(6)27(28(38)22-33)13-14-30-35(5)21-26(25-11-9-24(23-39)10-12-25)31(40)34(3,4)29(35)15-16-37(30,36)7/h9-13,21,28-30H,14-20,22H2,1-8H3/t28-,29-,30+,35-,36+,37+,38-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of IFN-gamma stimulated STAT3 (unknown origin) expressed in human HeLa cells after 6 hrs by luciferase reporter gene assay				J Nat Prod 80: 2276-2283 (2017) Article DOI: 10.1021/acs.jnatprod.7b00271 BindingDB Entry DOI: 10.7270/Q2VX0K32
					More data for this Ligand-Target Pair