BDBM50456775 CHEMBL4216220

SMILES: [H][C@@]12CCc3cc(C(C)C)c(cc3[C@@]1(C)CCC[C@@]2(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1

InChI Key: InChIKey=KDSZBJVBHXTOGE-HNLKLKQNSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50456775 (CHEMBL4216220) Show SMILES [H][C@@]12CCc3cc(C(C)C)c(cc3[C@@]1(C)CCC[C@@]2(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C50H56N4O5S/c1-34(2)40-32-37-26-27-45-49(3,28-17-29-50(45,4)48(57)53-42(30-35-18-9-5-10-19-35)46(55)51-38-22-13-7-14-23-38)41(37)33-44(40)60(58,59)54-43(31-36-20-11-6-12-21-36)47(56)52-39-24-15-8-16-25-39/h5-16,18-25,32-34,42-43,45,54H,17,26-31H2,1-4H3,(H,51,55)(H,52,56)(H,53,57)/t42-,43-,45+,49+,50+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of recombinant human MMP9 (Ala20 to Asp707 residues) expressed in CHO cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincub...				Eur J Med Chem 138: 979-992 (2017) Article DOI: 10.1016/j.ejmech.2017.07.020 BindingDB Entry DOI: 10.7270/Q2R49TBN
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50456775 (CHEMBL4216220) Show SMILES [H][C@@]12CCc3cc(C(C)C)c(cc3[C@@]1(C)CCC[C@@]2(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C50H56N4O5S/c1-34(2)40-32-37-26-27-45-49(3,28-17-29-50(45,4)48(57)53-42(30-35-18-9-5-10-19-35)46(55)51-38-22-13-7-14-23-38)41(37)33-44(40)60(58,59)54-43(31-36-20-11-6-12-21-36)47(56)52-39-24-15-8-16-25-39/h5-16,18-25,32-34,42-43,45,54H,17,26-31H2,1-4H3,(H,51,55)(H,52,56)(H,53,57)/t42-,43-,45+,49+,50+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of recombinant human MMP8 (Phe21 to Gly467 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrat...				Eur J Med Chem 138: 979-992 (2017) Article DOI: 10.1016/j.ejmech.2017.07.020 BindingDB Entry DOI: 10.7270/Q2R49TBN
					More data for this Ligand-Target Pair
Matrix metalloproteinase (2 and 3) (Homo sapiens (Human))	BDBM50456775 (CHEMBL4216220) Show SMILES [H][C@@]12CCc3cc(C(C)C)c(cc3[C@@]1(C)CCC[C@@]2(C)C(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C50H56N4O5S/c1-34(2)40-32-37-26-27-45-49(3,28-17-29-50(45,4)48(57)53-42(30-35-18-9-5-10-19-35)46(55)51-38-22-13-7-14-23-38)41(37)33-44(40)60(58,59)54-43(31-36-20-11-6-12-21-36)47(56)52-39-24-15-8-16-25-39/h5-16,18-25,32-34,42-43,45,54H,17,26-31H2,1-4H3,(H,51,55)(H,52,56)(H,53,57)/t42-,43-,45+,49+,50+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrat...				Eur J Med Chem 138: 979-992 (2017) Article DOI: 10.1016/j.ejmech.2017.07.020 BindingDB Entry DOI: 10.7270/Q2R49TBN
					More data for this Ligand-Target Pair