BDBM50457134 CHEMBL4213180

SMILES: C[C@H]1CN(C(=O)c2ccccc2)c2ccccc2N1C(C)=O

InChI Key: InChIKey=XISWKHNXRRASFZ-ZDUSSCGKSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50457134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50457134 (CHEMBL4213180) Show SMILES C[C@H]1CN(C(=O)c2ccccc2)c2ccccc2N1C(C)=O |r| Show InChI InChI=1S/C18H18N2O2/c1-13-12-19(18(22)15-8-4-3-5-9-15)16-10-6-7-11-17(16)20(13)14(2)21/h3-11,13H,12H2,1-2H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of His-epitope tagged BRD4 bromodomain 1 (44 to 168 residues) (unknown origin) using biotinylated K5,8,12,16 tetra-acetylated histone H4 (...				ACS Med Chem Lett 8: 847-852 (2017) Article DOI: 10.1021/acsmedchemlett.7b00191 BindingDB Entry DOI: 10.7270/Q2WQ06DS
					More data for this Ligand-Target Pair