BDBM50457864 CHEMBL4213363

SMILES: COc1ccc(NC(=O)N2C[C@H](C)N(C[C@H]2C)c2nc(N)nc3scnc23)cc1

InChI Key: InChIKey=IELPDCATGFILAL-NWDGAFQWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457864 (CHEMBL4213363) Show SMILES COc1ccc(NC(=O)N2C[C@H](C)N(C[C@H]2C)c2nc(N)nc3scnc23)cc1 |r| Show InChI InChI=1S/C19H23N7O2S/c1-11-9-26(19(27)22-13-4-6-14(28-3)7-5-13)12(2)8-25(11)16-15-17(29-10-21-15)24-18(20)23-16/h4-7,10-12H,8-9H2,1-3H3,(H,22,27)(H2,20,23,24)/t11-,12+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	381	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50457864 (CHEMBL4213363) Show SMILES COc1ccc(NC(=O)N2C[C@H](C)N(C[C@H]2C)c2nc(N)nc3scnc23)cc1 |r| Show InChI InChI=1S/C19H23N7O2S/c1-11-9-26(19(27)22-13-4-6-14(28-3)7-5-13)12(2)8-25(11)16-15-17(29-10-21-15)24-18(20)23-16/h4-7,10-12H,8-9H2,1-3H3,(H,22,27)(H2,20,23,24)/t11-,12+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
UCB Pharma Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...				J Med Chem 61: 6705-6723 (2018) Article DOI: 10.1021/acs.jmedchem.8b00521 BindingDB Entry DOI: 10.7270/Q2FF3W01
					More data for this Ligand-Target Pair