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SMILES: COc1ccc(cc1Cl)C1=NN(C2CCCC2)C(=O)C2CC=CCC12

InChI Key: InChIKey=HZXQJGPDTRZCNX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50457943 (CHEMBL4213295) Show SMILES COc1ccc(cc1Cl)C1=NN(C2CCCC2)C(=O)C2CC=CCC12 |c:23,t:10| Show InChI InChI=1S/C20H23ClN2O2/c1-25-18-11-10-13(12-17(18)21)19-15-8-4-5-9-16(15)20(24)23(22-19)14-6-2-3-7-14/h4-5,10-12,14-16H,2-3,6-9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of PDE4D3 (unknown origin) using [3H]cAMP as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...				Eur J Med Chem 146: 381-394 (2018) Article DOI: 10.1016/j.ejmech.2018.01.068 BindingDB Entry DOI: 10.7270/Q2XD1496
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50457943 (CHEMBL4213295) Show SMILES COc1ccc(cc1Cl)C1=NN(C2CCCC2)C(=O)C2CC=CCC12 |c:23,t:10| Show InChI InChI=1S/C20H23ClN2O2/c1-25-18-11-10-13(12-17(18)21)19-15-8-4-5-9-16(15)20(24)23(22-19)14-6-2-3-7-14/h4-5,10-12,14-16H,2-3,6-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of PDE7A1 (unknown origin) expressed in baculovirus infected insect cells using [3H]cAMP as substrate preincubated for 5 mins followed by ...				Eur J Med Chem 146: 381-394 (2018) Article DOI: 10.1016/j.ejmech.2018.01.068 BindingDB Entry DOI: 10.7270/Q2XD1496
					More data for this Ligand-Target Pair