null

SMILES: Cn1c2nc(NCc3ccccn3)n(CCCC(=O)N\N=C\c3ccccc3O)c2c(=O)n(C)c1=O

InChI Key: InChIKey=MQMDUXNYJBQCTF-MZJWZYIUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50457960 (CHEMBL4214541) Show SMILES Cn1c2nc(NCc3ccccn3)n(CCCC(=O)N\N=C\c3ccccc3O)c2c(=O)n(C)c1=O Show InChI InChI=1S/C24H26N8O4/c1-30-21-20(22(35)31(2)24(30)36)32(23(28-21)26-15-17-9-5-6-12-25-17)13-7-11-19(34)29-27-14-16-8-3-4-10-18(16)33/h3-6,8-10,12,14,33H,7,11,13,15H2,1-2H3,(H,26,28)(H,29,34)/b27-14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged PDE4B expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...				Eur J Med Chem 146: 381-394 (2018) Article DOI: 10.1016/j.ejmech.2018.01.068 BindingDB Entry DOI: 10.7270/Q2XD1496
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50457960 (CHEMBL4214541) Show SMILES Cn1c2nc(NCc3ccccn3)n(CCCC(=O)N\N=C\c3ccccc3O)c2c(=O)n(C)c1=O Show InChI InChI=1S/C24H26N8O4/c1-30-21-20(22(35)31(2)24(30)36)32(23(28-21)26-15-17-9-5-6-12-25-17)13-7-11-19(34)29-27-14-16-8-3-4-10-18(16)33/h3-6,8-10,12,14,33H,7,11,13,15H2,1-2H3,(H,26,28)(H,29,34)/b27-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged PDE7A expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...				Eur J Med Chem 146: 381-394 (2018) Article DOI: 10.1016/j.ejmech.2018.01.068 BindingDB Entry DOI: 10.7270/Q2XD1496
					More data for this Ligand-Target Pair