BDBM50458419 CHEMBL4203286

SMILES: CC(Oc1ccc(cc1)C#N)C(=O)OCc1cc(on1)-c1cccs1

InChI Key: InChIKey=UZZVNQUABWCEDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50458419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 2 (Homo sapiens (Human))	BDBM50458419 (CHEMBL4203286) Show SMILES CC(Oc1ccc(cc1)C#N)C(=O)OCc1cc(on1)-c1cccs1 Show InChI InChI=1S/C18H14N2O4S/c1-12(23-15-6-4-13(10-19)5-7-15)18(21)22-11-14-9-16(24-20-14)17-3-2-8-25-17/h2-9,12H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of human USP2a (258 to 605 residues) expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate incubated for 30 mins measured at 3...				Eur J Med Chem 150: 261-267 (2018) Article DOI: 10.1016/j.ejmech.2018.03.009 BindingDB Entry DOI: 10.7270/Q28G8P98
					More data for this Ligand-Target Pair