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BDBM50459065 CHEMBL4215760

SMILES: NC(=N)NC(=O)c1nc(-c2cc3ccccc3[nH]2)c(nc1N)N1CCCCCC1

InChI Key: InChIKey=YYMJBYORFXNXJN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50459065   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urokinase-type plasminogen activator/surface receptor


(Homo sapiens (Human))		BDBM50459065
PNG
(CHEMBL4215760)
Show SMILES NC(=N)NC(=O)c1nc(-c2cc3ccccc3[nH]2)c(nc1N)N1CCCCCC1
Show InChI InChI=1S/C20H24N8O/c21-17-16(19(29)27-20(22)23)25-15(14-11-12-7-3-4-8-13(12)24-14)18(26-17)28-9-5-1-2-6-10-28/h3-4,7-8,11,24H,1-2,5-6,9-10H2,(H2,21,26)(H4,22,23,27,29)
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PC cid
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Article
PubMed
 5.67E+3n/an/an/an/an/an/an/an/a



University of Wollongong

Curated by ChEMBL


Assay Description
Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assay

J Med Chem 61: 8299-8320 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00838
BindingDB Entry DOI: 10.7270/Q2QF8WH4
More data for this
Ligand-Target Pair